We see that you have javascript disabled. Please enable javascript and refresh the page to continue reading local news. If you feel you have received this message in error, please contact the customer support team at 1-833-248-7801.

Sponsored By

Sponsored By
An organization or individual has paid for the creation of this work but did not approve or review it.



Health Fusion: Why inflammatory arthritis attacks the same joints again and again

Can a disease like arthritis have a memory? It sure seems like it when flare-ups keep happening in the same joint. In this episode of NewsMD's "Health Fusion," Viv Williams shares info from a study that explores the memory power of inflammatory arthritis and related diseases.

We are part of The Trust Project.

This scenario is all too common for people with inflammatory arthritis. They get a major flare in the right knee and left wrist. Then it subsides, only to return to the same joints. Each patient develops a distinct disease pattern. But why?

Researchers from Boston Children's Hospital and Brigham and Women’s Hospital are trying to figure out why the disease seems to remember which joints have flared in the past. They did a study and found out where that memory lives: in a type of immune cell called a tissue-resident memory T cell. Those cells hide out in the synovium, which is the tissue that lines the capsule around the joint. After flares, the T-cells stay there and wait for another trigger.

The researchers say their data showed if you get rid of those cells, the flare-ups stop. That's huge and potentially very encouraging news for the many people who suffer from these ongoing, life-long and painful diseases. The researchers hope this new information will help to develop new and better treatments.

The study is published in the journal Cell Reports.

Follow the Health Fusion podcast on Apple , Spotify , and Google Podcasts.


For comments or other podcast episode ideas, email Viv Williams at vwilliams@newsmd.com . Or on Twitter/Instagram/FB @vivwilliamstv.

Health Fusion logo Sponsor 1400x1400

What to read next
For Fay Haataja the post-COVID program at Essentia Health helped her overcome debilitating headaches, brain fog and long-term memory loss after more than a year of symptoms.
Thanks to FDA approval, InForum columnist Carol Bradley Bursack notes that over-the-counter hearing aids are a new option for those suffering from hearing loss.
Town hall on health care in rural Minnesota looks into structural solutions for a looming crisis in outstate hospitals, one that could soon leave small towns struggling to provide the basics of care.
A dog's sense of smell has helped to find missing people, detect drugs at airports and find the tiniest morsel of food dropped from a toddler's highchair. A new study shows that dogs may also be able to sniff out when you're stressed out.